p53 functional states are associated with distinct aldehyde dehydrogenase transcriptomic signatures

p53 and aldehyde dehydrogenase (ALDH) have been implicated in key tumorigenesis processes including cancer initiating cell (CIC) maintenance; however, the relationship between these two mediators remains poorly defined. In this study, ALDH isoform expression diversity was revealed in CICs with dispa...

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Pubblicato in:Sci Rep
Autori principali: Gui, Shanying, Xie, Xiujie, O’Neill, Wendi Q., Chatfield-Reed, Kate, Yu, Jun-Ge, Teknos, Theodoros N., Pan, Quintin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978341/
https://ncbi.nlm.nih.gov/pubmed/31974410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57758-5
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