The Hyperpolarization-Activated Cyclic-Nucleotide-Gated Channel Blocker Ivabradine Does Not Prevent Arrhythmias in Catecholaminergic Polymorphic Ventricular Tachycardia

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited, stressed-provoked ventricular arrhythmia. CPVT is treated by β-adrenergic receptor blockers, Na(+) channel inhibitors, sympathetic denervation, or by implanting a defibrillator. We showed recently that blockers of SK4 Ca(2...

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Publicat a:Front Pharmacol
Autors principals: Bueno-Levy, Hanna, Weisbrod, David, Yadin, Dor, Haron-Khun, Shiraz, Peretz, Asher, Hochhauser, Edith, Arad, Michael, Attali, Bernard
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978284/
https://ncbi.nlm.nih.gov/pubmed/32009964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01566
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