Clonal hematopoiesis in elderly twins: concordance, discordance, and mortality

Clonal hematopoiesis (CH) of indeterminate potential (CHIP) is defined by mutations in myeloid cancer–associated genes with a variant allele frequency of at least 2%. Recent studies have suggested a possible genetic predisposition to CH. To further explore this phenomenon, we conducted a population-...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Hansen, Jakob Werner, Pedersen, Dorthe Almind, Larsen, Lisbeth Aagaard, Husby, Simon, Clemmensen, Signe Bedsted, Hjelmborg, Jacob, Favero, Francesco, Weischenfeldt, Joachim, Christensen, Kaare, Grønbæk, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978157/
https://ncbi.nlm.nih.gov/pubmed/31697811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001793
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