Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV

Establishment of viral latency is not only essential for lifelong Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, but it is also a prerequisite of viral tumorigenesis. The latent viral DNA has a complex chromatin structure, which is established in a stepwise manner regulated by host epigen...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Naik, Nenavath Gopal, Nguyen, Thomas Hong, Roberts, Lauren, Fischer, Luke Todd, Glickman, Katherine, Golas, Gavin, Papp, Bernadett, Toth, Zsolt
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977772/
https://ncbi.nlm.nih.gov/pubmed/31923286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008268
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