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Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV

Establishment of viral latency is not only essential for lifelong Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, but it is also a prerequisite of viral tumorigenesis. The latent viral DNA has a complex chromatin structure, which is established in a stepwise manner regulated by host epigen...

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書誌詳細
出版年:PLoS Pathog
主要な著者: Naik, Nenavath Gopal, Nguyen, Thomas Hong, Roberts, Lauren, Fischer, Luke Todd, Glickman, Katherine, Golas, Gavin, Papp, Bernadett, Toth, Zsolt
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977772/
https://ncbi.nlm.nih.gov/pubmed/31923286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008268
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