Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV

Establishment of viral latency is not only essential for lifelong Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, but it is also a prerequisite of viral tumorigenesis. The latent viral DNA has a complex chromatin structure, which is established in a stepwise manner regulated by host epigen...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Naik, Nenavath Gopal, Nguyen, Thomas Hong, Roberts, Lauren, Fischer, Luke Todd, Glickman, Katherine, Golas, Gavin, Papp, Bernadett, Toth, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977772/
https://ncbi.nlm.nih.gov/pubmed/31923286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008268
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