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Upregulation of flavin-containing monooxygenase 3 mimics calorie restriction to retard liver aging by inducing autophagy

Flavin-containing monooxygenase 3 (FMO3) gene expression is often upregulated in long-lived murine models. However, the specific relationship between FMO3 and aging remains unknown. Here, we show that 40% calorie restriction (CR), which is considered to be one of the most robust interventions to del...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Guo, Donghao, Shen, Yun, Li, Wei, Li, Qinjie, Miao, Ya, Zhong, Yuan
Format: Artigo
Language:Inglês
Published: Impact Journals 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977670/
https://ncbi.nlm.nih.gov/pubmed/31927537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102666
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