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Inhibition of Splicing Factor 3b Subunit 1 (SF3B1) Reduced Cell Proliferation, Induced Apoptosis and Resulted in Cell Cycle Arrest by Regulating Homeobox A10 (HOXA10) Splicing in AGS and MKN28 Human Gastric Cancer Cells

BACKGROUND: Small nuclear ribonucleoproteins (snRNPs) complexes of protein and noncoding RNA accumulate in the cell nucleus and catalyze pre-mRNA splicing to form the spliceosome. This study aimed to investigate the role of the spliceosome, splicing factor 3b subunit 1 (SF3B1), in AGS and MKN28 huma...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Zhang, Yan, Yuan, Zhen, Jiang, Yannan, Shen, Renbin, Gu, Menghui, Xu, Wei, Gu, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977614/
https://ncbi.nlm.nih.gov/pubmed/31927557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.919460
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