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Vaspin antagonizes high fat-induced bone loss in rats and promotes osteoblastic differentiation in primary rat osteoblasts through Smad-Runx2 signaling pathway

BACKGROUND: Visceral adipose tissue-derived serine protease inhibitor (vaspin), an adipose-derived hormone, exhibits various biological functions. Recently, studies showed that vaspin is closely related to bone metabolism. However, how vaspin influences bone formation and its underlying mechanisms i...

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Bibliografiske detaljer
Udgivet i:Nutr Metab (Lond)
Main Authors: Wang, Hongwei, Chen, Fulian, Li, Jiaxuan, Wang, Yan, Jiang, Chunyan, Zhang, Mengqi, Xu, Jin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977231/
https://ncbi.nlm.nih.gov/pubmed/31993071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-020-0429-5
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