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Next‐generation sequencing identifies a novel frameshift variant in FRMD7 in a Chinese family with idiopathic infantile nystagmus

BACKGROUND: Idiopathic infantile nystagmus (IIN) is a high genetically heterogeneous ophthalmic disease and is often associated with pathogenic mutations in FRMD7 and GPR143, respectively. Idiopathic infantile nystagmus manifests as involuntary periodic rhythmic oscillation of the eyes in the very e...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Wang, Fengqi, Guan, Hongzai, Liu, Wenmiao, Zhao, Guiqiu, Liu, Shiguo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977136/
https://ncbi.nlm.nih.gov/pubmed/31495972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23012
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