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Interferon Gamma Reprograms Host Mitochondrial Metabolism through Inhibition of Complex II To Control Intracellular Bacterial Replication

The mechanisms by which interferon gamma (IFN-γ) controls the replication of cytosolic pathogens independent of responses, such as the generation of reactive oxygen species/reactive nitrogen species (ROS/RNS), have not been fully elucidated. In the current study, we developed a model using Francisel...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Jessop, Forrest, Buntyn, Robert, Schwarz, Benjamin, Wehrly, Tara, Scott, Dana, Bosio, Catharine M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977132/
https://ncbi.nlm.nih.gov/pubmed/31740527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00744-19
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