CD40 Signaling in Macrophages Induces Activity against an Intracellular Pathogen Independently of Gamma Interferon and Reactive Nitrogen Intermediates

Gamma interferon (IFN-γ) is the major inducer of classical activation of macrophages. Classically activated mouse macrophages acquire antimicrobial activity that is largely dependent on the production of reactive nitrogen intermediates. However, protection against important intracellular pathogens c...

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Bibliographische Detailangaben
Hauptverfasser: Andrade, Rosa M., Portillo, Jose-Andres C., Wessendarp, Matthew, Subauste, Carlos S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087328/
https://ncbi.nlm.nih.gov/pubmed/15845519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.5.3115-3123.2005
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