CD40 Signaling in Macrophages Induces Activity against an Intracellular Pathogen Independently of Gamma Interferon and Reactive Nitrogen Intermediates

Gamma interferon (IFN-γ) is the major inducer of classical activation of macrophages. Classically activated mouse macrophages acquire antimicrobial activity that is largely dependent on the production of reactive nitrogen intermediates. However, protection against important intracellular pathogens c...

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Detalhes bibliográficos
Main Authors: Andrade, Rosa M., Portillo, Jose-Andres C., Wessendarp, Matthew, Subauste, Carlos S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087328/
https://ncbi.nlm.nih.gov/pubmed/15845519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.5.3115-3123.2005
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