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CD40 Signaling in Macrophages Induces Activity against an Intracellular Pathogen Independently of Gamma Interferon and Reactive Nitrogen Intermediates

Gamma interferon (IFN-γ) is the major inducer of classical activation of macrophages. Classically activated mouse macrophages acquire antimicrobial activity that is largely dependent on the production of reactive nitrogen intermediates. However, protection against important intracellular pathogens c...

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Autors principals: Andrade, Rosa M., Portillo, Jose-Andres C., Wessendarp, Matthew, Subauste, Carlos S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087328/
https://ncbi.nlm.nih.gov/pubmed/15845519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.5.3115-3123.2005
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