Combination Immunotherapy with Passive Antibody and Sulfasalazine Accelerates Fungal Clearance and Promotes the Resolution of Pneumocystis-Associated Immunopathogenesis

The pulmonary immune response protects healthy individuals against Pneumocystis pneumonia (PcP). However, the immune response also drives immunopathogenesis in patients who develop severe PcP, and it is generally accepted that optimal treatment requires combination strategies that promote fungal kil...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Hoy, Zachary, Wright, Terry W., Elliott, Michael, Malone, Jane, Bhagwat, Samir, Wang, Jing, Gigliotti, Francis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977122/
https://ncbi.nlm.nih.gov/pubmed/31611280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00640-19
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