Combination Immunotherapy with Passive Antibody and Sulfasalazine Accelerates Fungal Clearance and Promotes the Resolution of Pneumocystis-Associated Immunopathogenesis

The pulmonary immune response protects healthy individuals against Pneumocystis pneumonia (PcP). However, the immune response also drives immunopathogenesis in patients who develop severe PcP, and it is generally accepted that optimal treatment requires combination strategies that promote fungal kil...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Hoy, Zachary, Wright, Terry W., Elliott, Michael, Malone, Jane, Bhagwat, Samir, Wang, Jing, Gigliotti, Francis
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977122/
https://ncbi.nlm.nih.gov/pubmed/31611280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00640-19
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