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Relaxin reduces endothelium‐derived vasoconstriction in hypertension: Revealing new therapeutic insights

BACKGROUND AND PURPOSE: Endothelium‐derived vasoconstriction is a hallmark of vascular dysfunction in hypertension. In some cases, an overproduction of endothelium‐derived prostacyclin (PGI(2)) can cause contraction rather than relaxation. Relaxin is well known for its vasoprotective actions, but th...

詳細記述

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書誌詳細
出版年:Br J Pharmacol
主要な著者: Leo, Chen Huei, Ng, Hooi Hooi, Marshall, Sarah A., Jelinic, Maria, Rupasinghe, Thusitha, Qin, Chengxue, Roessner, Ute, Ritchie, Rebecca H., Tare, Marianne, Parry, Laura J.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976785/
https://ncbi.nlm.nih.gov/pubmed/31479151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14858
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