Relaxin reduces endothelium‐derived vasoconstriction in hypertension: Revealing new therapeutic insights

BACKGROUND AND PURPOSE: Endothelium‐derived vasoconstriction is a hallmark of vascular dysfunction in hypertension. In some cases, an overproduction of endothelium‐derived prostacyclin (PGI(2)) can cause contraction rather than relaxation. Relaxin is well known for its vasoprotective actions, but th...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Leo, Chen Huei, Ng, Hooi Hooi, Marshall, Sarah A., Jelinic, Maria, Rupasinghe, Thusitha, Qin, Chengxue, Roessner, Ute, Ritchie, Rebecca H., Tare, Marianne, Parry, Laura J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976785/
https://ncbi.nlm.nih.gov/pubmed/31479151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14858
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