Relaxin reduces endothelium‐derived vasoconstriction in hypertension: Revealing new therapeutic insights

BACKGROUND AND PURPOSE: Endothelium‐derived vasoconstriction is a hallmark of vascular dysfunction in hypertension. In some cases, an overproduction of endothelium‐derived prostacyclin (PGI(2)) can cause contraction rather than relaxation. Relaxin is well known for its vasoprotective actions, but th...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Leo, Chen Huei, Ng, Hooi Hooi, Marshall, Sarah A., Jelinic, Maria, Rupasinghe, Thusitha, Qin, Chengxue, Roessner, Ute, Ritchie, Rebecca H., Tare, Marianne, Parry, Laura J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976785/
https://ncbi.nlm.nih.gov/pubmed/31479151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14858
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