Relaxin reduces endothelium‐derived vasoconstriction in hypertension: Revealing new therapeutic insights

BACKGROUND AND PURPOSE: Endothelium‐derived vasoconstriction is a hallmark of vascular dysfunction in hypertension. In some cases, an overproduction of endothelium‐derived prostacyclin (PGI(2)) can cause contraction rather than relaxation. Relaxin is well known for its vasoprotective actions, but th...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Leo, Chen Huei, Ng, Hooi Hooi, Marshall, Sarah A., Jelinic, Maria, Rupasinghe, Thusitha, Qin, Chengxue, Roessner, Ute, Ritchie, Rebecca H., Tare, Marianne, Parry, Laura J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976785/
https://ncbi.nlm.nih.gov/pubmed/31479151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14858
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