High-risk blastemal Wilms tumor can be modeled by 3D spheroid cultures in vitro

In vitro models represent a critical tool in cancer research to study tumor biology and to evaluate new treatment options. Unfortunately, there are no effective preclinical models available that represent Wilms tumor (WT) — the most common pediatric renal tumor. Especially the high-risk blastemal WT...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Wegert, Jenny, Zauter, Lisa, Appenzeller, Silke, Otto, Christoph, Bausenwein, Sabrina, Vokuhl, Christian, Ernestus, Karen, Furtwängler, Rhoikos, Graf, Norbert, Gessler, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976522/
https://ncbi.nlm.nih.gov/pubmed/31562394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-1027-8
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