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Retinoic acid pathway activity in wilms tumors and characterization of biological responses in vitro

BACKGROUND: Wilms tumor (WT) is one of the most common malignancies in childhood. With current therapy protocols up to 90% of patients can be cured, but there is still a need to improve therapy for patients with aggressive WT and to reduce treatment intensity where possible. Prior data suggested a d...

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Bibliographic Details
Main Authors: Wegert, Jenny, Bausenwein, Sabrina, Kneitz, Susanne, Roth, Sabine, Graf, Norbert, Geissinger, Eva, Gessler, Manfred
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239322/
https://ncbi.nlm.nih.gov/pubmed/22067876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-136
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