A Randomized, Double‐Blinded, Phase II Trial of Carboplatin and Pemetrexed with or without Apatorsen (OGX‐427) in Patients with Previously Untreated Stage IV Non‐Squamous‐Non‐Small‐Cell Lung Cancer: The SPRUCE Trial

BACKGROUND. This randomized, double‐blinded, phase II trial evaluated the efficacy of carboplatin and pemetrexed plus either apatorsen, an antisense oligonucleotide targeting heat shock protein (Hsp) 27 mRNA, or placebo in patients with previously untreated metastatic nonsquamous non‐small cell lung...

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Xehetasun bibliografikoak
Argitaratua izan da:Oncologist
Egile Nagusiak: Spigel, David R., Shipley, Dianna L., Waterhouse, David M., Jones, Suzanne F., Ward, Patrick J., Shih, Kent C., Hemphill, Brian, McCleod, Michael, Whorf, Robert C., Page, Ray D., Stilwill, Joseph, Mekhail, Tarek, Jacobs, Cindy, Burris, Howard A., Hainsworth, John D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Inc. 2019
Gaiak:
Lung Cancer
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975937/
https://ncbi.nlm.nih.gov/pubmed/31420467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0518
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