A Randomized, Double‐Blinded, Phase II Trial of Gemcitabine and Nab‐Paclitaxel Plus Apatorsen or Placebo in Patients with Metastatic Pancreatic Cancer: The RAINIER Trial

LESSONS LEARNED. The addition of the heat shock protein 27 (Hsp27)‐targeting antisense oligonucleotide, apatorsen, to a standard first‐line chemotherapy regimen did not result in improved survival in unselected patients with metastatic pancreatic cancer. Findings from this trial hint at the possible...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Ko, Andrew H., Murphy, Patrick B., Peyton, James D., Shipley, Dianna L., Al‐Hazzouri, Ahmed, Rodriguez, Francisco A., Womack, Mark S., Xiong, Henry Q., Waterhouse, David M., Tempero, Margaret A., Guo, Shuangli, Lane, Cassie M., Earwood, Chris, DeBusk, Laura M., Bendell, Johanna C.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2017
Assuntos:
Clinical Trial Results
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728028/
https://ncbi.nlm.nih.gov/pubmed/28935773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0066
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