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A Randomized, Double‐Blinded, Phase II Trial of Gemcitabine and Nab‐Paclitaxel Plus Apatorsen or Placebo in Patients with Metastatic Pancreatic Cancer: The RAINIER Trial

LESSONS LEARNED. The addition of the heat shock protein 27 (Hsp27)‐targeting antisense oligonucleotide, apatorsen, to a standard first‐line chemotherapy regimen did not result in improved survival in unselected patients with metastatic pancreatic cancer. Findings from this trial hint at the possible...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Oncologist
Κύριοι συγγραφείς: Ko, Andrew H., Murphy, Patrick B., Peyton, James D., Shipley, Dianna L., Al‐Hazzouri, Ahmed, Rodriguez, Francisco A., Womack, Mark S., Xiong, Henry Q., Waterhouse, David M., Tempero, Margaret A., Guo, Shuangli, Lane, Cassie M., Earwood, Chris, DeBusk, Laura M., Bendell, Johanna C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: AlphaMed Press 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728028/
https://ncbi.nlm.nih.gov/pubmed/28935773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0066
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