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Allosteric response to ligand binding: Molecular dynamics study of the N-terminal domains in IP(3) receptor
Inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R) is a huge tetrameric intracellular Ca(2+) channel that mediates cytoplasmic Ca(2+) signaling. The structural basis of the gating in IP(3)R has been studied by X-ray crystallography and cryo-electron microscopy, focusing on the domain rearrangeme...
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| Udgivet i: | Biophys Physicobiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society of Japan (BSJ)
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6975907/ https://ncbi.nlm.nih.gov/pubmed/31984176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysico.16.0_232 |
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