Design and assessment of TRAP-CSP fusion antigens as effective malaria vaccines

The circumsporozoite protein (CSP) and thrombospondin-related adhesion protein (TRAP) are major targets for pre-erythrocytic malaria vaccine development. However, the CSP-based vaccine RTS,S provides only marginal protection, highlighting the need for innovative vaccine design and development. Here...

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Pubblicato in:PLoS One
Autori principali: Lu, Chafen, Song, Gaojie, Beale, Kristin, Yan, Jiabin, Garst, Emma, Feng, Juan, Lund, Emily, Catteruccia, Flaminia, Springer, Timothy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975556/
https://ncbi.nlm.nih.gov/pubmed/31967991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216260
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