A role of hypoxia-inducible factor 1 alpha in Murine Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latency

The hypoxia-inducible factor 1 alpha (HIF1α) protein and the hypoxic microenvironment are critical for infection and pathogenesis by the oncogenic gammaherpesviruses (γHV), Kaposi sarcoma herpes virus (KSHV) and Epstein-Barr virus (EBV). However, understanding the role of HIF1α during the virus life...

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Опубликовано в: :PLoS Pathog
Главные авторы: López-Rodríguez, Darlah M., Kirillov, Varvara, Krug, Laurie T., Mesri, Enrique A., Andreansky, Samita
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975554/
https://ncbi.nlm.nih.gov/pubmed/31809522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008192
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