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RTA Occupancy of the Origin of Lytic Replication during Murine Gammaherpesvirus 68 Reactivation from B Cell Latency

RTA, the viral Replication and Transcription Activator, is essential for rhadinovirus lytic gene expression upon de novo infection and reactivation from latency. Lipopolysaccharide (LPS)/toll-like receptor (TLR)4 engagement enhances rhadinovirus reactivation. We developed two new systems to examine...

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Bibliographic Details
Published in:Pathogens
Main Authors: Santana, Alexis L., Oldenburg, Darby G., Kirillov, Varvara, Malik, Laraib, Dong, Qiwen, Sinayev, Roman, Marcu, Kenneth B., White, Douglas W., Krug, Laurie T.
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371897/
https://ncbi.nlm.nih.gov/pubmed/28212352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens6010009
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