L-Citrulline increases nitric oxide and improves control in obese asthmatics

BACKGROUND: The airways of obese asthmatics have been shown to be NO deficient, and this contributes to airway dysfunction and reduced response to inhaled corticosteroids. In cultured airway epithelial cells, L-citrulline, a precursor of L-arginine recycling and NO formation, has been shown to preve...

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Foilsithe in:JCI Insight
Main Authors: Holguin, Fernando, Grasemann, Hartmut, Sharma, Sunita, Winnica, Daniel, Wasil, Karen, Smith, Vong, Cruse, Margaret H., Perez, Nancy, Coleman, Erika, Scialla, Timothy J., Que, Loretta G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2019
Ábhair:
Clinical Medicine
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975256/
https://ncbi.nlm.nih.gov/pubmed/31714895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131733
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