Bioenergetic Differences in the Airway Epithelium of Lean Versus Obese Asthmatics Are Driven by Nitric Oxide and Reflected in Circulating Platelets

Aims: Asthma, characterized by airway obstruction and hyper-responsiveness, is more severe and less responsive to treatment in obese subjects. While alterations in mitochondrial function and redox signaling have been implicated in asthma pathogenesis, it is unclear whether these mechanisms differ in...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Winnica, Daniel, Corey, Catherine, Mullett, Steven, Reynolds, Michael, Hill, Gabrielle, Wendell, Stacy, Que, Loretta, Holguin, Fernando, Shiva, Sruti
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Forum Original Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708272/
https://ncbi.nlm.nih.gov/pubmed/30608004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2018.7627
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