Involvement of Glutathione Depletion in Selective Cytotoxicity of Oridonin to p53-Mutant Esophageal Squamous Carcinoma Cells

Oridonin, a diterpenoid compound isolated from traditional Chinese medicine Rabdosia rubescens, has shown antitumor effects to esophageal cancer. However, its molecular mechanism is not fully understood, which limits its clinical application. In the present study, we used RNA-seq analysis to check t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Oncol
Päätekijät: Li, Yinchao, Li, Nana, Shi, Jianxiang, Ahmed, Tanzeel, Liu, Hongmin, Guo, Jiancheng, Tang, Wenxue, Guo, Yongjun, Zhang, Qi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2020
Aiheet:
Oncology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974803/
https://ncbi.nlm.nih.gov/pubmed/32010620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01525
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