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Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long‐lived and cancer‐resistant subterranean wild rodent, Spalax

The blind mole rat (Spalax) is a wild, long‐lived rodent that has evolved mechanisms to tolerate hypoxia and resist cancer. Previously, we demonstrated high DNA repair capacity and low DNA damage in Spalax fibroblasts following genotoxic stress compared with rats. Since the acquisition of senescence...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Odeh, Amani, Dronina, Maria, Domankevich, Vered, Shams, Imad, Manov, Irena
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974727/
https://ncbi.nlm.nih.gov/pubmed/31605433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13045
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