Lysophosphatidic acid receptor LPA(3) prevents oxidative stress and cellular senescence in Hutchinson–Gilford progeria syndrome

Hutchinson–Gilford progeria syndrome (HGPS) is a rare laminopathy that produces a mutant form of prelamin A, known as Progerin, resulting in premature aging. HGPS cells show morphological abnormalities of the nuclear membrane, reduced cell proliferation rates, accumulation of reactive oxygen species...

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書誌詳細
出版年:Aging Cell
主要な著者: Chen, Wei‐Min, Chiang, Jui‐Chung, Lin, Yueh‐Chien, Lin, Yu‐Nung, Chuang, Pei‐Yun, Chang, Ya‐Chi, Chen, Chien‐Chin, Wu, Kao‐Yi, Hsieh, Jung‐Chien, Chen, Shih‐Kuo, Huang, Wei‐Pang, Chen, Benjamin P. C., Lee, Hsinyu
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974717/
https://ncbi.nlm.nih.gov/pubmed/31714004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13064
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