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Lysophosphatidic acid receptor LPA(3) prevents oxidative stress and cellular senescence in Hutchinson–Gilford progeria syndrome
Hutchinson–Gilford progeria syndrome (HGPS) is a rare laminopathy that produces a mutant form of prelamin A, known as Progerin, resulting in premature aging. HGPS cells show morphological abnormalities of the nuclear membrane, reduced cell proliferation rates, accumulation of reactive oxygen species...
Kaydedildi:
| Yayımlandı: | Aging Cell |
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| Asıl Yazarlar: | , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6974717/ https://ncbi.nlm.nih.gov/pubmed/31714004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13064 |
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