Lysophosphatidic acid receptor LPA(3) prevents oxidative stress and cellular senescence in Hutchinson–Gilford progeria syndrome

Hutchinson–Gilford progeria syndrome (HGPS) is a rare laminopathy that produces a mutant form of prelamin A, known as Progerin, resulting in premature aging. HGPS cells show morphological abnormalities of the nuclear membrane, reduced cell proliferation rates, accumulation of reactive oxygen species...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Chen, Wei‐Min, Chiang, Jui‐Chung, Lin, Yueh‐Chien, Lin, Yu‐Nung, Chuang, Pei‐Yun, Chang, Ya‐Chi, Chen, Chien‐Chin, Wu, Kao‐Yi, Hsieh, Jung‐Chien, Chen, Shih‐Kuo, Huang, Wei‐Pang, Chen, Benjamin P. C., Lee, Hsinyu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974717/
https://ncbi.nlm.nih.gov/pubmed/31714004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13064
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