Non-ionizing 405 nm Light as a Potential Bactericidal Technology for Platelet Safety: Evaluation of in vitro Bacterial Inactivation and in vivo Platelet Recovery in Severe Combined Immunodeficient Mice

Bacterial contamination of ex vivo stored platelets is a cause of transfusion-transmitted infection. Violet-blue 405 nm light has recently demonstrated efficacy in reducing the bacterial burden in blood plasma, and its operational benefits such as non-ionizing nature, penetrability, and non-requirem...

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Detalles Bibliográficos
Publicado en:Front Med (Lausanne)
Autores principales: Maclean, Michelle, Gelderman, Monique P., Kulkarni, Sandhya, Tomb, Rachael M., Stewart, Caitlin F., Anderson, John G., MacGregor, Scott J., Atreya, Chintamani D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974518/
https://ncbi.nlm.nih.gov/pubmed/32010702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2019.00331
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