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Non-ionizing 405 nm Light as a Potential Bactericidal Technology for Platelet Safety: Evaluation of in vitro Bacterial Inactivation and in vivo Platelet Recovery in Severe Combined Immunodeficient Mice

Bacterial contamination of ex vivo stored platelets is a cause of transfusion-transmitted infection. Violet-blue 405 nm light has recently demonstrated efficacy in reducing the bacterial burden in blood plasma, and its operational benefits such as non-ionizing nature, penetrability, and non-requirem...

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Main Authors: Michelle Maclean, Monique P. Gelderman, Sandhya Kulkarni, Rachael M. Tomb, Caitlin F. Stewart, John G. Anderson, Scott J. MacGregor, Chintamani D. Atreya
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-01-01
Colecção:Frontiers in Medicine
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fmed.2019.00331/full
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