Enhanced Cell Division Is Required for the Generation of Memory CD4 T Cells to Migrate Into Their Proper Location

CD4 T cell memory is fundamental for long-lasting immunity and effective secondary responses following infection or vaccination. We have previously found that memory CD4 T cells specific for systemic antigens preferentially reside in the bone marrow (BM) and arise from splenic CD49b(+)T-bet(+) CD4 T...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sarkander, Jana, Hojyo, Shintaro, Mursell, Mathias, Yamasaki, Yuzuru, Wu, Tsung-Yen, Tumes, Damon J., Miyauchi, Kosuke, Tran, Cam Loan, Zhu, Jinfang, Löhning, Max, Hutloff, Andreas, Mashreghi, Mir-Farzin, Kubo, Masato, Radbruch, Andreas, Tokoyoda, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974474/
https://ncbi.nlm.nih.gov/pubmed/32010148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03113
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