Salmonella SiiE prevents an efficient humoral immune memory by interfering with IgG(+) plasma cell persistence in the bone marrow

Serum IgG, which is mainly generated from IgG-secreting plasma cells in the bone marrow (BM), protects our body against various pathogens. We show here that the protein SiiE of Salmonella is both required and sufficient to prevent an efficient humoral immune memory against the pathogen by selectivel...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Männe, Christian, Takaya, Akiko, Yamasaki, Yuzuru, Mursell, Mathias, Hojyo, Shintaro, Wu, Tsung-Yen, Sarkander, Jana, McGrath, Mairi A., Cornelis, Rebecca, Hahne, Stefanie, Cheng, Qingyu, Kawamoto, Tadafumi, Hiepe, Falk, Kaufmann, Stefan H. E., Yamamoto, Tomoko, Radbruch, Andreas, Tokoyoda, Koji
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2019
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462062/
https://ncbi.nlm.nih.gov/pubmed/30910977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818242116
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