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egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, causing immunosuppression, and hindering the immune response against bacterial in...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6974467/ https://ncbi.nlm.nih.gov/pubmed/32010128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03008 |
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