egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation

Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, causing immunosuppression, and hindering the immune response against bacterial in...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Noli Truant, Sofia, De Marzi, Mauricio C., Sarratea, María B., Antonoglou, María B., Meo, Ana P., Iannantuono López, Laura V., Fernández Lynch, María J., Todone, Marcos, Malchiodi, Emilio L., Fernández, Marisa M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974467/
https://ncbi.nlm.nih.gov/pubmed/32010128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03008
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