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Closed circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system: Development, technical evaluation and pulmonary effects

BACKGROUND: Therapeutic hypothermia (TH) for 72h is the standard treatment following neonatal encephalopathy (NE). However, one-third do not benefit and adjunctive therapies are urgently needed. Xenon enhances neuroprotection with TH when administered at 50% concentration within 5hours of hypoxia in...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Dingley, John, Okano, Satomi, Lee-Kelland, Richard, Scull-Brown, Emma, Thoresen, Marianne, Chakkarapani, Ela
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974042/
https://ncbi.nlm.nih.gov/pubmed/31961878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224447
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