Closed circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system: Development, technical evaluation and pulmonary effects

BACKGROUND: Therapeutic hypothermia (TH) for 72h is the standard treatment following neonatal encephalopathy (NE). However, one-third do not benefit and adjunctive therapies are urgently needed. Xenon enhances neuroprotection with TH when administered at 50% concentration within 5hours of hypoxia in...

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Pubblicato in:PLoS One
Autori principali: Dingley, John, Okano, Satomi, Lee-Kelland, Richard, Scull-Brown, Emma, Thoresen, Marianne, Chakkarapani, Ela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974042/
https://ncbi.nlm.nih.gov/pubmed/31961878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224447
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