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Hyperosmotic stress: in situ chromatin phase separation

Dehydration of cells by acute hyperosmotic stress has profound effects upon cell structure and function. Interphase chromatin and mitotic chromosomes collapse (“congelation”). HL-60/S4 cells remain ~100% viable for, at least, 1 hour, exhibiting shrinkage to ~2/3 their original volume, when placed in...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Olins, Ada L., Gould, Travis J., Boyd, Logan, Sarg, Bettina, Olins, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973338/
https://ncbi.nlm.nih.gov/pubmed/31924112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2019.1710321
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