The role of integrins in the pathogenesis of inflammatory bowel disease: Approved and investigational anti‐integrin therapies

Inflammatory bowel disease (IBD) is characterized by uncontrolled inflammation in the gastrointestinal tract. The underlying pathobiology of IBD includes an increase in infiltrating gut‐homing lymphocytes. Although lymphocyte homing is typically a tightly regulated and stepwise process involving mul...

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Bibliographic Details
Published in:Med Res Rev
Main Authors: Dotan, Iris, Allez, Matthieu, Danese, Silvio, Keir, Mary, Tole, Swati, McBride, Jacqueline
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Review Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973243/
https://ncbi.nlm.nih.gov/pubmed/31215680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21601
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