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The role of integrins in the pathogenesis of inflammatory bowel disease: Approved and investigational anti‐integrin therapies

Inflammatory bowel disease (IBD) is characterized by uncontrolled inflammation in the gastrointestinal tract. The underlying pathobiology of IBD includes an increase in infiltrating gut‐homing lymphocytes. Although lymphocyte homing is typically a tightly regulated and stepwise process involving mul...

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Dettagli Bibliografici
Pubblicato in:Med Res Rev
Autori principali: Dotan, Iris, Allez, Matthieu, Danese, Silvio, Keir, Mary, Tole, Swati, McBride, Jacqueline
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973243/
https://ncbi.nlm.nih.gov/pubmed/31215680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21601
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