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Assessment of the effects of immunogenicity on the pharmacokinetics, efficacy and safety of tildrakizumab
BACKGROUND: We evaluated antidrug antibody (ADA) development in patients with chronic plaque psoriasis from three clinical trials of tildrakizumab, a humanized anti‐interleukin‐23p19 monoclonal antibody (P05495, reSURFACE 1 and reSURFACE 2). OBJECTIVES: To determine the effects of immunogenicity on...
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| Udgivet i: | Br J Dermatol |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6972989/ https://ncbi.nlm.nih.gov/pubmed/30916381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjd.17918 |
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