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The Role of Peripheral Opioid Receptors in Triggering Heroin-induced Brain Hypoxia

While it is known that opioid receptors (ORs) are densely expressed in both the brain and periphery, it is widely accepted that hypoxic effects of opioids result solely from their direct action in the CNS. To examine the role of peripheral ORs in triggering brain hypoxia, we used oxygen sensors in f...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Perekopskiy, David, Afzal, Anum, Jackson, Shelley N., Muller, Ludovic, Woods, Amina S., Kiyatkin, Eugene A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972941/
https://ncbi.nlm.nih.gov/pubmed/31964994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57768-3
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