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The Role of Peripheral Opioid Receptors in Triggering Heroin-induced Brain Hypoxia

While it is known that opioid receptors (ORs) are densely expressed in both the brain and periphery, it is widely accepted that hypoxic effects of opioids result solely from their direct action in the CNS. To examine the role of peripheral ORs in triggering brain hypoxia, we used oxygen sensors in f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Perekopskiy, David, Afzal, Anum, Jackson, Shelley N., Muller, Ludovic, Woods, Amina S., Kiyatkin, Eugene A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972941/
https://ncbi.nlm.nih.gov/pubmed/31964994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57768-3
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