Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis

Chaperonin-containing TCP-1 (CCT or TRiC) is a multi-subunit complex that folds many of the proteins essential for cancer development. CCT is expressed in diverse cancers and could be an ideal therapeutic target if not for the fact that the complex is encoded by eight distinct genes, complicating th...

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Publicado en:Sci Rep
Autores principales: Showalter, Anne E., Martini, Ana C., Nierenberg, Daniel, Hosang, Kristen, Fahmi, Naima Ahmed, Gopalan, Priya, Khaled, Amr S., Zhang, Wei, Khaled, Annette R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972895/
https://ncbi.nlm.nih.gov/pubmed/31964905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57602-w
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