Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis

Chaperonin-containing TCP-1 (CCT or TRiC) is a multi-subunit complex that folds many of the proteins essential for cancer development. CCT is expressed in diverse cancers and could be an ideal therapeutic target if not for the fact that the complex is encoded by eight distinct genes, complicating th...

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Foilsithe in:Sci Rep
Main Authors: Showalter, Anne E., Martini, Ana C., Nierenberg, Daniel, Hosang, Kristen, Fahmi, Naima Ahmed, Gopalan, Priya, Khaled, Amr S., Zhang, Wei, Khaled, Annette R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972895/
https://ncbi.nlm.nih.gov/pubmed/31964905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57602-w
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