Induction of left ventricular hypoplasia by occluding the foramen ovale in the fetal lamb

Disturbed fetal haemodynamics often affects cardiac development and leads to congenital cardiac defects. Reduced left ventricular (LV) preload in the fetus may result in hypoplastic LV, mitral and aortic valve, mimicking a moderate form of hypoplastic left heart complex. We aimed to induce LV hypopl...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wong, Flora Y., Veldman, Alex, Sasi, Arun, Teoh, Mark, Edwards, Andrew, Chan, Yuen, Graupner, Oliver, Enzensberger, Christian, Axt-Fliedner, Roland, Black, Mary Jane, Schranz, Dietmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972793/
https://ncbi.nlm.nih.gov/pubmed/31964989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57694-4
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