Induction of left ventricular hypoplasia by occluding the foramen ovale in the fetal lamb

Disturbed fetal haemodynamics often affects cardiac development and leads to congenital cardiac defects. Reduced left ventricular (LV) preload in the fetus may result in hypoplastic LV, mitral and aortic valve, mimicking a moderate form of hypoplastic left heart complex. We aimed to induce LV hypopl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wong, Flora Y., Veldman, Alex, Sasi, Arun, Teoh, Mark, Edwards, Andrew, Chan, Yuen, Graupner, Oliver, Enzensberger, Christian, Axt-Fliedner, Roland, Black, Mary Jane, Schranz, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972793/
https://ncbi.nlm.nih.gov/pubmed/31964989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57694-4
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