Genetic variants in IL17A and serum levels of IL-17A are associated with COPD related to tobacco smoking and biomass burning

IL-17A is an important pro-inflammatory cytokine involved in the inflammatory response in chronic obstructive pulmonary disease (COPD). To evaluate the role played by single nucleotide polymorphisms of IL17A and protein levels in susceptibility to COPD, 1,807 subjects were included in a case-control...

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Vydáno v:Sci Rep
Hlavní autoři: Ponce-Gallegos, Marco A., Pérez-Rubio, Gloria, Ambrocio-Ortiz, Enrique, Partida-Zavala, Neftali, Hernández-Zenteno, Rafael, Flores-Trujillo, Fernando, García-Gómez, Leonor, Hernández-Pérez, Andrea, Ramírez-Venegas, Alejandra, Falfán-Valencia, Ramcés
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972744/
https://ncbi.nlm.nih.gov/pubmed/31964947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57606-6
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