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Genetic variants in IL17A and serum levels of IL-17A are associated with COPD related to tobacco smoking and biomass burning

IL-17A is an important pro-inflammatory cytokine involved in the inflammatory response in chronic obstructive pulmonary disease (COPD). To evaluate the role played by single nucleotide polymorphisms of IL17A and protein levels in susceptibility to COPD, 1,807 subjects were included in a case-control...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ponce-Gallegos, Marco A., Pérez-Rubio, Gloria, Ambrocio-Ortiz, Enrique, Partida-Zavala, Neftali, Hernández-Zenteno, Rafael, Flores-Trujillo, Fernando, García-Gómez, Leonor, Hernández-Pérez, Andrea, Ramírez-Venegas, Alejandra, Falfán-Valencia, Ramcés
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972744/
https://ncbi.nlm.nih.gov/pubmed/31964947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57606-6
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